It includes what’s called demyelination which is damage to myelin, the protective coating that helps to protect nerve cells in the central nervous system.Īlthough CIS doesn’t necessarily lead to MS, it could be an early sign.

doi: 10.5664/jcsm.Common early signs of multiple sclerosis (MS) include:įor some people, the earliest signs of MS might include clinically isolated syndrome (CIS), neurologic symptoms that last at least 24 hours and can’t be associated with another cause. Impact of the COVID-19 pandemic on obstructive sleep apnea: recommendations for symptom management. The pandemic causes us to reflect that the provisional targeting of symptoms and guidance regarding mitigation strategies while waiting for specialist care could serve patients well at any time.” REFERENCE Rizzo D, Libman E, Baltzman M, Fichten C. They also addressed potential post-pandemic uses of identifying and mitigating OSA with this strategy, writing that “as sleep clinic services resume, we can expect even longer wait times as the backlog of patients will need to be addressed. However, recommending behavioral interventions poses no risk to the patient,” Rizzo and colleagues wrote. Weighted analyses showed that some items on the SSC subscale are more important than others.

“Our results show that the SSC is an acceptable tool to identify potential OSA and use to make recommendations to improve sleep during the pandemic. Using the 4 SSC subscales together (insomnia, daytime symptoms, sleep disorders, and psychological maladjustment) as predictors in a discriminant analysis yielded a correct classification of 69.3% of patients into OSA and control groups. 638) were the dominating variables of the subscale and had a canonical correlation of 0.51 between the sets of variables ( P <.001). 834), “falling asleep during the day when not wanted” (r 2 =. The researchers found that “interruption of breathing” (r 2 =. These include interruption of breathing during sleep, snoring, unwanted falling asleep during the day, waking up with a dry mouth, and waking up with a headache. Rizzo and colleagues determined factors that physicians can question patients on that should prompt behavioral interventions and mitigation strategies until the patient can see a specialist. No PSG indices were associated with sleep disorder-related symptoms in the control group. 216 P <.01), oxygenation-basal oxygen value (r 2 = –.173 P <.05), and oxygenation-minimal oxygen value (r 2 =. 178 P <.02), respiratory events (Apnea Hypopnea Index r 2 =. 245 P <.01), spontaneous arousals (r 2 =. 204 P <.05), respiratory arousals (r 2 =. 179 P <.05), percentage of sleep time in stage 1 sleep (r 2 =. The researchers found that sleep disorder-related symptoms were positively correlated with several polysomnography (PSG) indices such as percentage of sleep time in rapid eye movement (REM) sleep (r 2 =. LISTEN NOW: Episode 30: Cognitive Behavioral Therapy for Insomnia They also recruited 60 control participants from the community with a mean age of 52.93 years (SD, 12.40), 36 (60%) of which were women. The mean age of patients was 56.66 years (standard deviation, 10.93). Rizzo and colleagues selected 156 family medicine patients from a larger ongoing prospective study, 88 (56%) of which were women. As such, they sought to determine how patients can be identified for possible OSA while sleep clinic testing is temporarily unavailable or limited and what measures can be suggested to improve sleep health until proper diagnosis and treatment become safe and available again. The authors noted the difficulty of conducting such studies during the pandemic, especially given the possibility of further outbreaks or shutdown orders. “Typically, individuals with OSA are identified through reported symptoms and overnight sleep studies,” first author Dorrie Rizzo, PhD, department of family medicine, McGill University, and colleagues wrote. They also had significantly more severe sleep-related symptoms than the control group. The study found that people with OSA reported more symptoms on the SSC related to insomnia, daytime symptoms, sleep disorders, and psychological maladjustment than the control group did ( P <.001). The results of a recent study suggest that general practitioners can effectively prescreen patients for possible obstructive sleep apnea (OSA) by inquiring about 5 items on the Sleep Symptom Checklist (SSC) sleep disorders subscale.

Ms symptoms checklist female